Review



aicar chemical  (Toronto Research Chemicals)


Bioz Verified Symbol Toronto Research Chemicals is a verified supplier
Bioz Manufacturer Symbol Toronto Research Chemicals manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 90

    Structured Review

    Toronto Research Chemicals aicar chemical
    Aicar Chemical, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/aicar+chemical/10__13005_slash_bpj_slash_2865-50-7-13
    Average 90 stars, based on 1 article reviews
    aicar chemical - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    Concentration Assay:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Cell Culture:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Activation Assay:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Clinical Proteomics:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Incubation:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Control:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Comparison:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Expressing:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Extraction:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Activity Assay:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Western Blot:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Cytometry:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Muscles:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Isolation:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Ex Vivo:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Phospho-proteomics:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Immunoprecipitation:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Introduce:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Generated:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Sterility:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Saline:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Injection:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Nuclear Magnetic Resonance:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Staining:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Real-time Polymerase Chain Reaction:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Reverse Transcription Polymerase Chain Reaction:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    TUNEL Assay:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Labeling:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Enzyme-linked Immunosorbent Assay:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.

    Transfection:

    Article Title: TBC1D4-S711 Controls Skeletal Muscle Insulin Sensitization After Exercise and Contraction.
    Article Snippet: After 10 min preincubation in KRB, muscles were incubated for 30 min in KRB containing AICAR (2 mmol/L) (Toronto Research Chemicals, Toronto, Ontario, Canada) or insulin (100 or 10,000 mU/mL) (Actrapid; Novo Nordisk, Denmark).

    Article Title: Serum Is Not Necessary for Prior Pharmacological Activation of AMPK to Increase Insulin Sensitivity of Mouse Skeletal Muscle
    Article Snippet: In short, EDL muscles were incubated for 50 min in the absence or presence of 1 mmol/L AICAR (Toronto Research Chemicals, Toronto, ON, Canada) in KRB or 100% human serum.

    Article Title: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Attenuates High Fat, High Fructose Diet-induced Fatty Liver and Fibrosis in Mice.
    Article Snippet: Chemicals, kits and animal food components AICAR, casein and fructose were purchased from Toronto Research Chemicals, Toronto, Ontario, Canada, Clarion Casein Pvt.

    Article Title: A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts
    Article Snippet: For AICAr treatment experiments, cells were maintained for 7 days with Plasmax-PV medium containing 25 nM of FA and AICAr (Toronto Research Chemicals, TRC, A611700) was added at the appropriate concentration during the last 24 h.

    Article Title: AMPK is elevated in human cachectic muscle and prevents cancer-induced metabolic dysfunction in mice
    Article Snippet: AICAR (Toronto Research Chemicals Inc., Toronto, 300mg/kg body mass in sterile saline) or sterile saline were administered via a subcutaneous injection at 4pm to 16 weeks old male C57BL/6JRj mice (Janvier Labs, France).

    Article Title: Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells.
    Article Snippet: The AMP-activated protein kinase (AMPK) pathway has been shown to be able to regulate inflammation in several cell lines.. We reported that fenoterol, a b2-adrenergic receptor (b2-AR) agonist, inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells, a monocytic cell line in previous studies.. 5-amino-1-b-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) is an agonist of AMPK.

    Article Title: The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN)
    Article Snippet: Every other day, the HFD mice received i.p. injections of PBS or AICAR (350 mg/kg) (Toronto Research Chemicals Inc., Toronto, Canada).

    Article Title: The human AMPKγ3 R225W mutation does neither enhance basal AMPKγ3-associated activity nor glycogen in human or mouse skeletal muscle
    Article Snippet: Furthermore, in a separate study, EDL muscles were isolated and treated with either basal, 0.25 mM or 2.0 mM AICAR (Toronto Research Chemicals, Canada) for 40 minutes.



    Similar Products

    94
    Cayman Chemical resource source identifier rad52 inhibitor aicar cayman chemical 10010241
    Resource Source Identifier Rad52 Inhibitor Aicar Cayman Chemical 10010241, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/AICAR/pm41785087-710-2-8
    Average 94 stars, based on 1 article reviews
    resource source identifier rad52 inhibitor aicar cayman chemical 10010241 - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    90
    Cayman Chemical aicar chemical
    Aicar Chemical, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/aicar+chemical/pm40233740-300-1-15
    Average 90 stars, based on 1 article reviews
    aicar chemical - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    96
    Selleck Chemicals chemical compounds 5 aminoimidazole 4 carboxamide 1 β d ribonucleoside
    Chemical Compounds 5 Aminoimidazole 4 Carboxamide 1 β D Ribonucleoside, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/AICAR/pm40329626-63-6-10
    Average 96 stars, based on 1 article reviews
    chemical compounds 5 aminoimidazole 4 carboxamide 1 β d ribonucleoside - by Bioz Stars, 2026-09
    96/100 stars
      Buy from Supplier

    97
    MedChemExpress chemical treatment
    Chemical Treatment, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/AICAR/pm39747484-428-1-16
    Average 97 stars, based on 1 article reviews
    chemical treatment - by Bioz Stars, 2026-09
    97/100 stars
      Buy from Supplier

    90
    Morishita Jintan aicar chemical
    Aicar Chemical, supplied by Morishita Jintan, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/aicar+chemical/10__1007_slash_s40005___024___00702___w-322-0-24
    Average 90 stars, based on 1 article reviews
    aicar chemical - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    90
    Toronto Research Chemicals aicar chemical
    Aicar Chemical, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/aicar+chemical/10__13005_slash_bpj_slash_2865-50-7-13
    Average 90 stars, based on 1 article reviews
    aicar chemical - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    90
    Millipore ffa chemicals, aicar, and the ahr inhibitor ch- 223191
    Ffa Chemicals, Aicar, And The Ahr Inhibitor Ch 223191, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/ch223191/10__7554_slash_elife__87458-272-3-13
    Average 90 stars, based on 1 article reviews
    ffa chemicals, aicar, and the ahr inhibitor ch- 223191 - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    92
    Toronto Research Chemicals aicar a611700 toronto research chemicals bay
    Aicar A611700 Toronto Research Chemicals Bay, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside/pmc10690046__mcr___23___0502_table_s1_suppst1-0-0-2
    Average 92 stars, based on 1 article reviews
    aicar a611700 toronto research chemicals bay - by Bioz Stars, 2026-09
    92/100 stars
      Buy from Supplier

    94
    Cayman Chemical carboxamide aicar cayman chemical
    Carboxamide Aicar Cayman Chemical, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aicar+chemical/AICAR/pm37726258-61-42-44
    Average 94 stars, based on 1 article reviews
    carboxamide aicar cayman chemical - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    Image Search Results